Joseph Grzymski

Assistant Research Professor

Division of Earth and Ecosystem Sciences

Email: joeg@dri.edu

Education

Professional Experience

• Assistant Research Professor, Desert Research Institute, Reno, NV
• Postdoctoral Associate, Desert Research Institute, Reno, NV
• Postdoctoral Associate, Rockefeller University, New York, NY

Current Research Projects

• Modeling and testing new methods in the design of novel drug targets
• Quantifying first principles of genome architecture in pathogens and free-living microbes
• International Polar Year: Bacterioplankton genomic adaptations to Antarctic Winter (PIs, Dr. Alison Murray, Dr. Hugh Ducklow
• Defining the universal patterns of environmental adaptation in microbial genomes (with Dr. Adam Marsh)

Field Experience

2006	Mt. Erebus and Miers Valley, Antarctica	Boating on the Antarctic Peninsula, 2003
2005	Mammoth Hot Springs, Yellowstone National Park
2004	Extreme 2004 Hydrothermal Vent Cruise, East Pacific Rise
2004	Long Term Ecological Research Cruise, Antarctic Peninsula
2003	Extreme 2003 Hydrothermal Vent Cruise, East Pacific Rise
2002	Santa Barbara Basin Cruise
2001	Palmer Station, Antarctica
2000	McMurdo Station, Antarctica
1999	European Large Scale Mesocosm Facility, Trondheim, Norway
1999	Long Term Ecosystem Observatory (LEO), New Jersey continental shelf
1998	Long Term Ecosystem Observatory (LEO), New Jersey continental shelf
1997	Long Term Ecosystem Observatory (LEO), New Jersey continental shelf
1996	Long Term Ecosystem Observatory (LEO), New Jersey continental shelf
1995	Svalbard, Norway and Arctic Ocean

Selected Publications

Soo RM, Wood SA, Grzymski JJ, McDonald IR, Cary SC. 2009.

Microbial biodiversity of thermophilic communities in hot mineral soils of Tramway Ridge, Mount Erebus, Antarctica. Env. Microbiol. 11(3):715-728.

Grzymski JJ, Murray AE, Campbell BJ, Kaplarevic M, Gao GR, Lee C, Daniel R, Ghadiri A, Feldman RA,

and Cary SC. 2008. Metagenome analysis of an extreme microbial symbiosis reveals eurythermal adaptation and metabolic flexibility. Proc Natl Acad Sci USA. 105(45) 17516-17521.

Marsh AG and Grzymski JJ. 2008.

System, method and identification of antibiotic drug targeting sites in proteins of pathogenic bacteria. Invention Disclosure.

Liu Y, Edens GJ, Grzymski J, Mauzerall D. 2008.

Volume and enthalpy changes of proton transfers in the bacteriorhodopsin photocycle studied by millisecond time-resolved photopressure measurements Biochem. 47(29) 7752-7761.

Murray, A. and Grzymski, J.J. 2007

Diversity and genomics of Antarctic marine microorganisms. Phil Trans R Soc B 362(1488) 2259-2272.

Grzymski, J.J., Carter, B., DeLong, E., Feldman, R., Ghadiri, A., Murray, A., 2006.

Comparative analysis of genome fragments from 6 uncultured Antarctic marine, planktonic bacteria reveals widespread amino acid modification towards cold adaptation. Appl. Env. Micro. 72(2) 1532-41.

Mauzerall D, Liu Y, Edens GJ, Grzymski, J. 2003.

Measurement of enthalpy and volume changes in photoinitiated reactions on the ms timescale with a novel pressure cell. Photoch. Photobio. Sci. 2 (7): 788-790.

Edens, G.J, Liu, Y., Grzymski, J., and Mauzerall, D. 2002.

Pressure cell for time-resolved calorimetric measurements of photo-initiated reactions on the fractional millisecond and longer time scale. Review of Scientific Instruments.74(4)2523-2529.

Grzymski, J., Schofield, O., Bernhard, J., and Falkowski, P. 2002.

The function of plastids in the deep-sea benthic foraminifer, Nonionella stella. Limnology and Oceanography. 47: 1569-1580. http://www.aslo.org/lo/toc/vol_47/issue_6/1569.pdf

Grzymski J. Moline MA, and Cullen JT. 2002.

Modeling the atmosphere/ocean CO2 cycle in relation to surface iron concentrations. In: Modeling Dynamic Systems: Dynamic Modeling for Marine Conservation. Lindholm J. and Ruth M. (eds) Springer Verlag 125-143.

Full CV (PDF)